The sections of the body that have fairly vulnerable superficial delicate anatomical structures that can be easily damaged are called endangerment sites, and when these sites are being treated, the therapist needs to be careful to adjust pressure and avoid prolonged pressure, as well as slowly, and lightly massaging the area surrounding the site. Energy work and other techniques that use very little pressure (like therapeutic touch) are exceptions to this directive. Specific sites that are endangered include nerves, blood vessels, bony structures, abnormal findings, organs, glands, abdomen, axilla, elbow, face, femoral triangle and medial thigh, low back, popliteal, and the throat.

The popliteal is an endangerment site that is found at the back of the knee. It is made up of the common peroneal, tibial nerves, as well as the popliteal arteries.

Two regions shaped triangularly make up the throat. These regions, the anterior and posterior cervical triangles (classified by the trachea, the bottom of the mandible, and the sternocleidomastoid) hold the anterior cervical triangles (made up of the common carotid arteries, external carotid arteries, hyoid bone, internal jugular veins, thyroid gland, trachea, and vagus nerves, which are seven sites of endangerment). The posterior cervical triangle, on the other hand, is identifiably made up of the clavicle, sternocleidomastoid, and trapezius. The endangerment sites of this region contain the brachial plexus, the external jugular veins, the facial nerves - posterior to the mandibular ramus, subclavian artery, and temporal bone styloid processes.